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#1
05-13-2010, 01:46 PM
 Redmolly Guest Posts: n/a
converting ng/ML to pmol/L

Can anyone help convert 2.0 ng/ML to pmol/L?

I'm trying to understand some test results but most information I've read is based on pmol/L and my test results are in ng/ML.

Any help would be appreciated!

Thanks!
#2
05-13-2010, 02:05 PM
 JohnS Moderator Join Date: Dec 2007 Location: SE Michigan, USA Posts: 9,446 Rep Power: 19
Re: converting ng/ML to pmol/L

Quote:
 Originally Posted by Redmolly Can anyone help convert 2.0 ng/ML to pmol/L? I'm trying to understand some test results but most information I've read is based on pmol/L and my test results are in ng/ML. Any help would be appreciated! Thanks!
Well, the milliliters to liters is easy, just multiply by 1000 mL/1 L.

To convert between grams and moles (regardless of prefixes) you have to know what the substance is and its its molar mass (numerically equal to the molecular weight). If you don't know that, you can't convert.
#3
05-13-2010, 09:27 PM
 Redmolly Guest Posts: n/a
Re: converting ng/ML to pmol/L

Thanks JohnS. The substance is AMH (Anti-Mullerian Hormone). For the molecular weight, all I have to go by is something I found doing a Google search for "Anti-Mullerian Hormone Molecular Weight". This is what I found:

"AMH is a homodimeric disulphide-linked glycoprotein with a molecular weight of 140 kDa"

Does that help at all? Its like reading Greek to me, so sorry I can't be more clear!
#4
05-14-2010, 02:57 AM
 JohnS Moderator Join Date: Dec 2007 Location: SE Michigan, USA Posts: 9,446 Rep Power: 19
Re: converting ng/ML to pmol/L

Quote:
 Originally Posted by Redmolly Thanks JohnS. The substance is AMH (Anti-Mullerian Hormone). For the molecular weight, all I have to go by is something I found doing a Google search for "Anti-Mullerian Hormone Molecular Weight". This is what I found: "AMH is a homodimeric disulphide-linked glycoprotein with a molecular weight of 140 kDa" Does that help at all? Its like reading Greek to me, so sorry I can't be more clear!
Thanks. The dalton is equivalent to the unified atomic mass unit. I'm sure that's "Greek" but it is the unit for measuring molecular weight, the "k" as usual means 1000. So the molar mass is 140000 g/mol or 140 kg/mol.

2 ng/mL x 1000 mL/1 L x 1 mol/140 kg = 14.3 pmol/L
(the medical part is all Greek to me, but that's the conversion. For any other substance, the second conversion factor changes with molecular weight)
#5
05-20-2010, 01:40 PM
 Unregistered Guest Posts: n/a
Re: converting ng/ML to pmol/L

Thanks again John. This was really helpful!
#6
06-11-2010, 05:44 AM
 Unregistered Guest Posts: n/a
Re: converting ng/ML to pmol/L

Hi John S

I'm hoping you might be able to help me out with a similar query, but converting the other way, from pmol/L to ng/ml

It's the same substance as above, but registering at 2.95pmol/L

Thanks
Helen
#7
06-11-2010, 11:41 AM
 JohnS Moderator Join Date: Dec 2007 Location: SE Michigan, USA Posts: 9,446 Rep Power: 19
Re: converting ng/ML to pmol/L

Quote:
 Originally Posted by Unregistered Hi John S I'm hoping you might be able to help me out with a similar query, but converting the other way, from pmol/L to ng/ml It's the same substance as above, but registering at 2.95pmol/L Thanks Helen
You just reverse the above. By keeping units attached to the numbers you can determine whether to divide or multiply. If you are doing it right, the unwanted units cancel

2.95 pmol/L X 1 L/1000 mL x 140 kg/1 mol = 0.413 ng/mL

Edit: Typo corrected from "2.95 pmol/M" to "2.95 pmol/L". The math was correct.

Last edited by JohnS; 11-05-2011 at 03:20 AM.
#8
06-11-2010, 12:39 PM
 Unregistered Guest Posts: n/a
Re: converting ng/ML to pmol/L

Brilliant. Thank you
#9
09-20-2011, 05:14 AM
 Unregistered Guest Posts: n/a
Re: converting ng/ML to pmol/L

Hello John S

You seem to be the expert here. I would be so grateful if you could convert 3.2pmol/l to ng/ML - again, the same substance so the same weight.

I know you've set out the formula but I'm afraid it's beyond me to apply it.

Hoping you can help

E
#10
09-20-2011, 07:01 AM
 JohnS Moderator Join Date: Dec 2007 Location: SE Michigan, USA Posts: 9,446 Rep Power: 19
Re: converting ng/ML to pmol/L

Quote:
 Originally Posted by Unregistered Hello John S You seem to be the expert here. I would be so grateful if you could convert 3.2pmol/l to ng/ML - again, the same substance so the same weight. I know you've set out the formula but I'm afraid it's beyond me to apply it. Hoping you can help E
3.2 pmol/L X 1 L/1000 mL x 140 kg/1 mol = 448 pg/mL or 0.448 ng/mL

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